Play Ball ⚾️

04/07/2022 Play Ball ⚾️

By: Jeff Yoder

2022 MLB Opening Day: World Series Odds & Every Game on the Schedule

Despite 99 days of a baseball lockout, Opening Day has finally arrived. The 2022 MLB season hung in limbo through much of the winter, but today’s first pitch at Wrigley Field kickstarts a full 162-game season with new rules and new lineups. The wildest free-agent frenzy in league history came storming in after the lockout ended, and baseball is back. Let’s take a look at the Opening Day slate and which teams have the best preseason odds to win the World Series.


Preseason World Series Odds

Dodgers (+500), Blue Jays (+800), Braves (+900), Astros (+1000), Yankees (+1100), White Sox (+1200), Mets (+1400), Rays (+1500), Brewers (+1600), Padres (+1800) | Full World Series Odds


Opening Day Schedule

Brewers at Cubs (2:20 pm)

Mets at Nationals (4:05 pm)

Guardians at Royals (4:10 pm)

Pirates at Cardinals (4:15 pm)

Reds at Braves (8:08 pm)

Astros at Angels (9:38 pm)

Padres at Diamondbacks (9:40 pm)


*All Times ET


Additional Storylines

SI: Yankees Postpone Opening Day Game Against Red Sox Due to Weather

MLB: Everything You Need to Know for the 2022 MLB Season Ahead

CBS Sports: 2022 MLB Predictions: Expert Picks for Division Winners & World Series Champion


Photo: Newsday LLC / Getty Images